General Information

  • ID:  hor006802
  • Uniprot ID:  A2VB89??24-153)
  • Protein name:  Bursicon
  • Gene name:  burs
  • Organism:  Apis mellifera
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Hymenoptera; Apocrita (wasps; ants; and bees); Aculeata; Apoidea (bees); Apidae (bumble bees and honey bees); Apinae (honey bees); Apini; Apis; Apis mellifera (Honeybee)
  • GO MF:  GO:0005576 extracellular region; GO:0005615 extracellular space
  • GO BP:  GO:0005179 hormone activity; GO:0036122 BMP binding
  • GO CC:  GO:0048067 cuticle pigmentation; GO:0038098 sequestering of BMP from receptor via BMP binding; GO:0009887 animal organ morphogenesis; GO:0005179; F:hormone activity; IMP:UniProtKB.; GO:0007593 chitin-based cuticle sclerotization

Sequence Information

  • Sequence:  IGVDECQATPVIHFLQYPGCVPKPIPSYACRGRCSSYLQVSGSKIWQMERSCMCCQESGEREASVSLFCPRAKPGEKKFRKVITKAPLECMCRPCTSVEEYAIIPQEIAGFADEGPFTTSAHFRRSSDLQ
  • Length:  130
  • Propeptide:  MLLYHIVGASVLICLLNETAKAIIGVDECQATPVIHFLQYPGCVPKPIPSYACRGRCSSYLQVSGSKIWQMERSCMCCQESGEREASVSLFCPRAKPGEKKFRKVITKAPLECMCRPCTSVEEYAIIPQEIAGFADEGPFTTSAHFRRSSDLQ
  • Signal peptide:  MLLYHIVGASVLICLLNETAKA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Bursicon as a heterodimer made of two cystine knot polypeptides plays an important role in the tanning of the exoskeleton and the newly occurring wing expansion behavior... emerged adult insects.
  • Mechanism:  Bursicon as a heterodimer made of two cystine knot polypeptides plays an important role in the tanning of the exoskeleton and the newly occurring wing expansion behavior... emerged adult insects.
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    NA

Physical Information

Mass: Formula:
Absent amino acids: Common amino acids:
pI: Basic residues:
Polar residues: Hydrophobic residues:
Hydrophobicity: Boman Index:
Half-Life: Half-Life Yeast:
Half-Life E.Coli: Aliphatic Index
Instability Index: Extinction Coefficient cystines:
Absorbance 280nm:

Literature

  • PubMed ID:  NA
  • Title:  NA